Nanoparticles have aided in the development of medicines including synthetic silver nanoparticles, that have extraordinary antibacterial properties. As a result of their antiseptic properties, silver nanoparticles are finding increasing use in the medical field, particularly in the treatment of bacterial infections. The chemical synthesis, biosynthesis, and antibacterial properties of silver nanoparticles have already been studied. however, due to the high cost of their chemical synthesis and the increase in the resistance of bacteria to antibiotics, it is very important to investigate the biosynthesis of silver nanoparticles and their effect on clinical and standard strains of various bacteria.
Nano silver is one of the most significant and useful nanoparticles, and it is currently being utilised in a variety of industries. Silver nanoparticles are also utilised in the packaging sector. When we need protection from impact, bacteria, and dirt on the material we want, we package and cover it. Numerous items need to be eliminated due to their bacterial associations, including foods, pharmaceutical coatings, medical equipment, surfaces that we frequently come into contact with in public, and many more. However, the largest area that needs to be antibacterial is food. An excellent choice for these applications would be silver nanoparticles that can combine and composite with polymers. Up to four times more than usual, this kind of packaging keeps food and vegetables healthy and fresh. It stopped 98 % of the bacteria and fungi from growing during tests that were done within the first 24 hours. 
Silver nanoparticles synthesis
A transmission electron microscope was used to examine the size and size distribution of the synthesis silver nanoparticles after they had been produced using two different methods, chemical reduction and biosynthesis with bacterial supernatant. The biosynthesis method using bacteria is a low-cost method, but it creates polydisperse nanoparticles. Considering the good antibacterial activity, silver nanoparticles can be a suitable alternative to antibiotics, but it should be noted that the resistance of clinical strains is higher compared to standard strains. The method of producing nanoparticles biologically has garnered interest due to its advantages, including simplicity, low cost, and environmental compatibility. Due to the lack of toxic and polluting materials, using plants to create nanoparticles is regarded as one of the environmentally friendly processes. It appears that using plant extracts during the green synthesis of nanoparticles can enhance their antibacterial properties.
In the current study, it was demonstrated that the extracts containing nanoparticles significantly improved their antibacterial properties. At room temperature, flavonoids and other water-soluble active metabolites, such as other bioactive substances and compounds found in plant extracts, can reduce metal ions to nanoparticles. The green production or the biosynthesis method is regarded as one of the cleanest, least expensive, lowest-risk, and most environmentally friendly synthesis methods for nanoparticle production. Due to the lack of hazardous chemicals used in this process and the effects of the silver nanoparticles obtained by using this plant's extract on human health, silver nanoparticles produced by this method have the potential to be used in industries related to human health, such as healthcare. These substances are an excellent substitute for antibiotics because of their antibacterial properties and lack of resistance to microorganisms. The most striking characteristic of these particles is their dual toxicity, which means that while they exhibit toxic effects on bacteria, they are also biocompatible to the body. 
Silver nanoparticles in medicine
Nanotechnology and silver nanoparticles have entered the field of health due to the advancements it has made in the field of medical care for preventative purposes. Nanotechnology has allowed for the early diagnosis of diseases and the halting of their progression. The health industry is expected to experience one of the fastest rates of nanotechnology growth over the coming ten years. The nano medicine market is currently established. Nano medicine has already produced several notable products where the nano dimensions have a particular impact on product efficacy, in contrast to some other potential applications of nanotechnology which are still largely in research. To eradicate bacteria, stronger antibiotics have to be used due to human and animal pathogens and antibiotic-resistant bacteria. which makes the use and production of antibiotics risky and unprofitable every day. Silver nanoparticles' functional mechanism makes them able to stop the growth of bacteria and the production of pathogens.
650 different types of viruses, including AIDS, can be eliminated by these materials, which have high stability and longevity. These substances are also used in the treatment of wounds, the coating of vascular prostheses and intravenous catheters with silver nanoparticles, and dressings and ointments. Additionally, the production of biosensors to detect diseases like cancer as well as the plasmonic properties of silver nanoparticles that can be used in medical imaging and plasmonic sensors, as well as the manufacturing of medical equipment that needs antibacterial materials. Large-scale research and development initiatives with a focus on drug delivery are currently being seen in the market. The greatest potential for nanotechnology diagnostic applications is in high-resolution imaging. Research is still needed for other applications, like coatings, implants, and advanced wound care in medicine, to help with the process of commercialization on a large scale. 
Silver nanoparticles properties
Silver nanoparticles are having a greater impact on human life than ever due to their numerous applications and advantageous properties in many industries. In addition to having antibacterial properties, silver nanoparticles also have properties that make them antifungal, anti-inflammatory, environmentally friendly, non-stimulating, non-allergenic, non-resistance to microorganisms, heat resistant, and highly stable. Like other biomaterials, silver nanoparticles can have toxic effects on living things. These particles' characteristics and entry points affect how toxic they are. Oxidative stress, which builds up in the cytoplasm and nucleus of the cell and causes the production of free radicals, is what causes the toxicity brought on by silver nanoparticles. Due to their high contact surface, silver nanoparticles that are initially formed as separate particles have the highest level of toxicity. However, as time goes on and they come together, their level of toxicity decreases. Silver nanoparticles having beneficial properties are being used in various applications for enhancing different products. 
Silver nanoparticles antibacterial
Smaller silver nanoparticles with antibacterial properties, obtained from chemical reduction had good activity against gram-negative and gram-positive bacteria and prevented the growth of all bacteria at a concentration of 0.2 mM, but larger nanoparticles had much less activity. The development of antibacterial materials thanks to nanosilver technology, which has many advantages over chemicals and is the primary direction for the expansion of nanosilver products, has been greatly accelerated. Silver has long been used because of its antimicrobial qualities, which have been known for a very long time. With the development of technology and the creation of silver nanoparticles, its antibacterial properties have significantly improved. Silver nanoparticles' increased surface-to-volume ratio has resulted in a significant increase in their ability to inhibit microbial growth and bacterial growth. Since the discovery of penicillin and other antibiotics, the use of silver has significantly decreased. However, in recent years, thanks to the development of nanosilver's antibacterial properties, interest in this substance have increased. Although there has been a significant rise in bacterial resistance to antibiotics, the introduction of nanosilver to the antibacterials field has rekindled optimism that bacteria can still be defeated. One more application for them today is in antibacterial dressings. The design of these dressings eliminates the need for antiseptics like betadine and lessens the risk of wound infection. 
Silver nanoparticles uses
The various uses of silver nanoparticles as drug and gene carriers is one of the most important applications of silver nanoparticles. This is because, in addition to increasing the entry of these compounds into the body, nanoparticles create synergistic effects against microorganisms and increase efficiency. The properties that silver nanoparticles possess make them desirable for use in the textile industry as well. In the field of textiles, one of their most well-known applications is the production of odourless, stain- and water-resistant nano clothing. The bacteria that live inside of shoes are one of the primary contributors to foot odour. These bacteria can rapidly reproduce due to the damp environment that exists inside of shoes, which in turn results in a foul odour. These bacteria are eliminated by silver, which also eliminates the foul foot odour they produce. In addition, silver nanoparticles are utilised in the process of water purification. Nanoparticles can be suspended in water in this manner, which leads to the destruction of microbes such as bacteria, fungi, and viruses. The particles are frequently used in wound dressings, wound dressings, and all other devices involved in the healing process for wounds because of their antibacterial properties.
It is extremely beneficial to use these particles in biosensors to detect and treat diseases like cancer. Furthermore, silver is used in catheters and vascular prostheses to reduce cladogenesis while boosting bacterial resistance. The use of silver nanoparticles in biosensors is another application that can be mentioned. The dielectric properties of these particles in biosensors make it possible to detect disorders and diseases (such as cancer). The plasmonic properties of silver nanoparticles have caused them to be used in medical imaging and plasmonic sensors. Silver nanoparticles can be used as a coating for vascular prostheses and intravenous catheters, which is one of the many applications of these particles that can be very useful. We can improve the manufacturing processes of a wide variety of products and increase the effectiveness of those processes thanks to the application of nanotechnology and nanoparticles. Our business has been quite successful over these years by providing a wide selection of nanoproducts and nanomaterials to our customers.
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